Sinomenine Hydrochloride Powder
Sinomenium Hydrochloride jẹ ohun elo kemikali ti o wa lati inu ọgbin Sinomenium acutum, eyiti o wọpọ ni Ila-oorun Asia. O jẹ alkaloid ti a ti lo ni aṣa ni oogun Kannada fun egboogi-iredodo ati awọn ohun-ini analgesic. Fọọmu hydrochloride jẹ iyọ ti o mu isodipupo ati iduroṣinṣin pọ si, ti o jẹ ki o dara julọ fun lilo oogun.
Sinomenine Hydrochloride ni a ti ṣe iwadi fun awọn ipa itọju ailera ti o pọju ni itọju awọn ipo bii arthritis rheumatoid, nitori agbara rẹ lati ṣe atunṣe eto ajẹsara ati dinku igbona. O ṣiṣẹ nipa didi iṣelọpọ ti awọn cytokines pro-inflammatory ati awọn olulaja miiran ti o ni ipa ninu idahun iredodo.
Ni afikun si egboogi-iredodo ati awọn ipa analgesic, Sinomenine Hydrochloride ti tun ṣe afihan agbara ni neuroprotection, egboogi-fibrosis, ati awọn iṣẹ egboogi-egbogi ni ọpọlọpọ awọn ẹkọ iṣaaju.
Orukọ Laiṣe: (9a,13a,14a) -7,8-didehydro-4-hydroxy-3,7-dimethoxy-17-methyl-morphinan-6-ọkan, monohydrochloride
Nọmba CAS: 6080-33-7
Awọn itumọ ọrọ: Cucoline NSC 76021
Fọọmu Molecular: C19H23NO4 • HCl
Iwọn agbekalẹ: 365.9
Mimo:≥98% Omi-lile kan
Solubility(Kọ ẹkọ nipa Iyatọ ni Solubility)
DMF: 30 mg/ml
DMSO: 30 mg/ml
Ethanol: 5 mg/ml
PBS (pH 7.2): 5 mg/ml
Ipilẹṣẹ: Ohun ọgbin/Sinomenium acutum
Gbigbe & Alaye Ibi ipamọ:
Ibi ipamọ -20 °C
Gbigbe: Iwọn otutu yara
Iduroṣinṣin: ≥ 4 ọdun
| Nkan | Sipesifikesonu | Abajade |
| Ayẹwo (HPLC) | 98.0% | 98.12% |
| Ifarahan | funfun Powder | Ibamu |
| Patiku Iwon | 98% nipasẹ 80mesh | Ibamu |
| Òórùn | Iwa | Ibamu |
| Lenu | Iwa | Ibamu |
| Awọn abuda ti ara | ||
| Isonu lori Gbigbe | ≤0.5% | 0.38% |
| Eeru | ≤0.5% | 0.46% |
| Awọn irin ti o wuwo | ||
| Awọn irin ti o wuwo (bii Pb) | Awọn ajohunše USP (<10ppm) | <10ppm |
| Arsenic(Bi) | ≤2ppm | 0.78ppm |
| Asiwaju (Pb) | ≤2ppm | 1.13pm |
| Cadmium(Cd) | ≤lppm | 0.36ppm |
| Mercary(Hg) | ≤0.1pm | 0.01pm |
| Ajẹkù ipakokoropaeku | Ti kii ṣe awari | Ti kii ṣe awari |
| Lapapọ PlateCount | NMT 10000cfu/g | 680 cfu/g |
| Apapọ iwukara &Mold | NMT 100cfu/g | 87 cfu/g |
| E.Coli | NMT 30cfu/g | 10 cfu/g |
| Salmonella | Odi | Odi |
| Ipari | Ni ibamu si Standard Enterprise | |
Awọn ipa akọkọ ti Sinomenine Hydrochloride pẹlu:
(1) Anti-iredodo: Din iredodo dinku.
(2) Analgesic: Pese iderun irora.
(3) Imunosuppressive: Npa iṣẹ ṣiṣe eto ajẹsara dinku.
(4) Anti-rheumatic: Ṣe itọju arthritis rheumatoid.
(5) Neuroprotective: Ṣe aabo awọn sẹẹli ara lati ibajẹ.
(6) Anti-fibrotic: Idilọwọ tabi dinku fibrosis tissu.
Sinomenine Hydrochloride jẹ lilo akọkọ ni awọn agbegbe wọnyi:
(1) Rheumatology: Itoju ti arthritis rheumatoid.
(2) Itọju irora: Ilọkuro ti irora irora.
(3) Anti-iredodo: Idinku iredodo.
(4) Immunomodulation: Iyipada ti eto ajẹsara.
(5) Neuroprotection: O pọju lilo ninu awọn itọju ailera neuroprotective.
Ilana iṣelọpọ ti Sinomenine Hydrochloride Powder le ṣe akopọ bi atẹle:
Igbaradi Ewebe:Ninu ati gbigbe awọn ohun elo ọgbin aise.
Iyọkuro:Lilo awọn olomi bii ethanol lati yọ sinomenine kuro ninu ohun elo ọgbin.
Ifojusi:Yiyọ epo kuro lati ṣojumọ akoonu sinomenine.
Alkalization:Ṣatunṣe pH lati yi sinomenine pada si fọọmu iyọ rẹ.
Isediwon Olomi-omi:Mimo pẹlu Organic olomi bi anisole tabi 1-heptanol.
Fifọ:Fifọ olomi lati yọ awọn aimọ ati awọn itọpa olomi kuro.
Asiitisi:Dinku pH lati ṣaju sinomenine hydrochloride.
Crystallization:Ṣiṣe awọn kirisita ti sinomenine hydrochloride.
Iyapa:Centrifuging tabi sisẹ lati ya awọn kirisita kuro ninu ojutu.
Gbigbe:Yiyọ ọrinrin to ku lati awọn kirisita.
Milling:Lilọ awọn kirisita ti o gbẹ sinu erupẹ ti o dara.
Sise:Aridaju aṣọ patiku iwọn pinpin.
Iṣakoso Didara:Idanwo fun mimọ, ifọkansi, ati awọn iṣedede microbiological.
Iṣakojọpọ:Ni ifo ati apoti to ni aabo fun pinpin.
Ibi ipamọ: Tọju ni itura, gbẹ, ati aaye mimọ, Dabobo lati ọrinrin ati ina taara.
Olopobobo Package: 25kg / ilu.
Akoko asiwaju: Awọn ọjọ 7 lẹhin aṣẹ rẹ.
Igbesi aye selifu: ọdun 2.
Akiyesi: Awọn pato ti a ṣe adani tun le ṣaṣeyọri.
KIAKIA
Labẹ 100kg, awọn ọjọ 3-5
Iṣẹ ilekun si ẹnu-ọna rọrun lati gbe awọn ẹru naa
Nipa Okun
Ju 300kg, ni ayika awọn ọjọ 30
Ibudo si ibudo iṣẹ alagbata alamọdaju nilo
Nipa Afẹfẹ
100kg-1000kg, 5-7days
Papa ọkọ ofurufu si alagbata alamọdaju iṣẹ papa ọkọ ofurufu nilo
Bioway Organic ti gba USDA ati EU Organic, BRC, ISO, HALAL, KOSHER, ati awọn iwe-ẹri HACCP.
