Stephania Fa Cepharanthine Powder

Orukọ ọja: Stephania Japonica Extract
Orisun Latin: Stephania cephalantha Hayata(Stephania japonica (Thunb.) Miers)/ Stephania epigaea Lo/ Stephania yunnanensis HSLo.
Irisi: funfun, grẹy White Powder
Eroja ti nṣiṣe lọwọ: Cepharanthine 80% -99% HPLC
Apakan Lo: Tuber/Root
Ohun elo: Awọn ọja ilera
Ojutu yo: 145-155°
Yiyi ni pato: D20+277°(c=2inchloroform)
Ojutu farabale: 654.03°C (iṣiro ti o ni inira)
iwuwo: 1.1761 (iṣiro ti o ni inira)
Atọka itọka: 1.5300 (iṣiro)
Awọn ipo ipamọ: underinertgas (nitrogen tabi Argon) ni 2-8 ° C
Solubility: Soluble ni SO (35mg/ml) tabi ethanol (20mg/ml)
Olusọdipúpọ acidity (pKa): 7.61 ± 0.20 (Asọtẹlẹ)


Alaye ọja

Awọn alaye miiran

ọja Tags

Ọja Ifihan

Stephania Extract Cepharanthine Powder jẹ nkan ti o wa lati awọn isu ti ọgbin Stephania cephalantha Hayata (Stephania japonica (Thunb.) Miers) tabi Stephania epigaea Lo/ Stephania yunnanensis HSLo. Cepharanthine jẹ ọja adayeba ti o ya sọtọ lati inu ọgbin yii ati pe o ti jẹ koko-ọrọ ti ọpọlọpọ awọn ijinlẹ nitori awọn ohun-ini elegbogi ti o pọju. O ti rii lati ṣafihan awọn iṣẹ egboogi-SARS-CoV-2, ti n ṣafihan imunadoko ni didapa itankale ọlọjẹ. Ni afikun, Cepharanthine ti ṣe afihan agbara lati yiyipada P-glycoprotein (P-gp) -aabo idawọle olopobobo ninu awọn sẹẹli kan ati mu ifamọ ti awọn aṣoju anticancer ni awọn awoṣe idanwo. Pẹlupẹlu, o ti han lati ni awọn ipa ti o ni idiwọ lori ẹdọ cytochrome P450 awọn enzymu CYP3A4, CYP2E1, ati CYP2C9, ati pe o ni nkan ṣe pẹlu antitumor, egboogi-iredodo, ati awọn ipa antinociceptive.
Ni akojọpọ, Stephania Extract Cepharanthine Powder jẹ fọọmu ti o ni erupẹ ti ọja adayeba Cepharanthine ti o wa lati inu ọgbin Stephania cephalantha, eyiti o ti ṣe afihan agbara ni orisirisi awọn ohun elo oogun.

Sipesifikesonu (COA)

Ọja Cepharanthine
CAS 481-49-2
Ayẹwo 80% ~ 99%
Ifarahan funfun lulú
Iṣakojọpọ 1KG/Apo bankanje
Nkan Sipesifikesonu
Ifarahan grẹy funfun lulú, didoju wònyí, gíga hygroscopic
Idanimọ TLC: Ojutu boṣewa ati ojutu idanwo aaye kanna, RF
Ayẹwo (Ipilẹ gbigbẹ) 98.0% --102.0%
Specific Optical -2.4°~ -2.8°
PH 4.5 ~ 7.0
Awọn irin Heavy (Bi Pb) ≤10ppm
As ≤1ppm
Pb ≤0.5ppm
Cd ≤1ppm
Hg ≤0.1pm
Ohun elo ti o jọmọ Aami ko tobi ju aaye ojutu boṣewa lọ
Aseku epo <0.5%
Omi akoonu <2%

Ọja Awọn ẹya ara ẹrọ

Stephania Extract Cepharanthine Powder jẹ ọja adayeba ti o wa lati inu ọgbin Stephania cephalantha Hayata. O ti rii pe o ni ọpọlọpọ awọn ohun-ini elegbogi, pẹlu:
1. Anti-SARS-CoV-2 akitiyan
2. Awọn ipa idinamọ lori ilọsiwaju ti gbogun ti
3. Iyipada ti P-glycoprotein-mediated multidrug resistance
4. Imudara ifamọ si awọn aṣoju anticancer
5. Awọn ipa idiwọ lori ẹdọ cytochrome P450 awọn enzymu CYP3A4, CYP2E1, ati CYP2C9
6. Antitumor, egboogi-iredodo, ati awọn ipa antinociceptive

Kini Biosynthesis ti Cepharanthine?

Biosynthesis ti cepharanthine ni Stephania bẹrẹ pẹlu ifasilẹ ti dopamine ati 4-hydroxyphenylacetaldehyde (4-HPAA, 5) nipasẹ norcoclaurine synthase (NCS), ti nso norcoclaurine.

Kini Solubility ti Cepharanthine?

Cepharanthine jẹ tiotuka ninu awọn nkan ti ara ẹni gẹgẹbi ethanol, DMSO, ati dimethyl formamide (DMF). Solubility ti cepharanthine ninu awọn olomi wọnyi jẹ isunmọ 2, 5, ati 10 mg/ml, lẹsẹsẹ. Cepharanthine jẹ tiotuka diẹ ninu awọn buffer olomi.

Awọn ohun elo

Awọn ile-iṣẹ ohun elo fun Stephania Extract Cepharanthine Powder pẹlu Pharmaceutical, Nutraceutical, Biotechnology, and Herbal Medicine, awọn ohun elo akọkọ jẹ bi atẹle:
O pọju lilo ni antiviral awọn itọju ailera
O pọju bi oluranlọwọ ni itọju akàn
O pọju fun lilo ninu awọn itọju egboogi-iredodo
O pọju bi oluranlowo analgesic
Awọn ohun elo wọnyi ṣe afihan awọn lilo agbara oniruuru ti Stephania Extract Cepharanthine Powder ni orisirisi awọn ipo itọju ailera.


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